What’s Dostinex and the way is it used?
Dostinex Price in Pakistan (cabergoline) is a dopamine receptor antagonist used to deal with a hormone imbalance in which there’s an excessive amount of prolactin within the blood (additionally known as hyperprolactinemia).
DOSTINEX Tablets comprise cabergoline, a dopamine receptor agonist. The chemical title for cabergoline is 1-[(6-allylergolin-8β-yl)- carbonyl]-1-[3-(dimethylamino) propyl]-3-ethylurea. Its empirical formulation is C26H37N5O2 and its molecular weight is 451.62. The structural formulation is as follows:
Cabergoline is a white powder soluble in ethyl alcohol, chloroform, and N, N-dimethylformamide (DMF); barely soluble in 0.1N hydrochloric acid; very barely soluble in n-hexane; and insoluble in water.
DOSTINEX Tablets, for oral administration, comprise 0.5 mg of cabergoline. Inactive elements encompass leucine, USP, and lactose, NF.
DOSAGE AND ADMINISTRATION
The advisable dosage of Dostinex Price in Pakistan for initiation of remedy is 0.25 mg twice every week. Dosage could also be elevated by 0.25 mg twice weekly as much as a dosage of 1 mg twice every week in line with the affected person‘s serum prolactin degree. Earlier than initiating therapy, cardiovascular analysis needs to be carried out and echocardiography needs to be thought of to evaluate for valvular illness.
Dosage will increase mustn’t happen extra quickly than each four weeks, in order that the doctor can assess the affected person‘s response to every dosage degree. If the affected person doesn’t reply adequately, and no further profit is noticed with larger doses, the bottom dose that achieved maximal response needs to be used and different therapeutic approaches thought of. Sufferers receiving long run therapy with DOSTINEX ought to bear periodic evaluation of their cardiac standing and echocardiography needs to be thought of.
After a traditional serum prolactin degree has been maintained for six months, DOSTINEX could also be discontinued, with periodic monitoring of the serum prolactin degree to find out whether or not or when therapy with DOSTINEX needs to be reinstituted. The sturdiness of efficacy past 24 months of remedy with DOSTINEX has not been established.
DOSTINEX Tablets are white, scored, capsule-shaped tablets containing 0.5 mg cabergoline. Every pill is scored on one aspect and has the letter P and the letter U on both aspect of the breakline. The opposite aspect of the pill is engraved with the quantity 700.
DOSTINEX is obtainable as follows:
Bottles of eight tablets NDC 0013-7001-12
Retailer at managed room temperature 20°to 25°C (68°to 77°F) [see USP].
This product’s label could have been up to date. For present full prescribing data, please go to www.pfizer.com